Mona Lisa: the different meanings of Leonardo’s masterpiece
April 24, 2026

From her enigmatic smile to the identity of Lisa Gherardini, here is what the Mona Lisa (La Gioconda) truly represents and why she continues to fascinate the world today.

The Mona Lisa is among the most famous and debated works by Leonardo da Vinci, a painting that encapsulates identity, technique, symbolism, and perception. The meaning of the Mona Lisa stems primarily from the figure represented, identified as Lisa Gherardini, whom Leonardo rendered so complex as to transcend a simple private portrait. Her enigmatic smile, achieved through the sfumato technique, changes depending on the viewer’s gaze and has fueled artistic, psychological, and scientific interpretations. Even the background landscape is more than decorative; it contributes to the sense of mystery and the relationship between humanity and nature, sparking numerous hypotheses regarding its specific location. Furthermore, the Mona Lisa reflects Renaissance values such as balance, harmony, and the centrality of the individual, but pushes them further by introducing a new level of inner depth.

TABLE OF CONTENT

Who is the Mona Lisa, really?

The lack of definitive documentation certifying the identity of the Gioconda left room for various hypotheses for a long time, some even suggesting that the Mona Lisa was Leonardo’s lover.

In reality, according to the most authoritative sources, the painting depicts Lisa Gherardini, wife of the Florentine merchant Francesco del Giocondo. This identification is currently the most widely accepted and is confirmed by the Musée du Louvre, which defines the work as the portrait of Lisa Gherardini.

A significant contribution to this theory came from a discovery at the Heidelberg University Library: a 1503 handwritten note by Agostino Vespucci links Leonardo specifically to a portrait of Lisa del Giocondo, strengthening this interpretation.

Inside Leonardo’s World

Experience interactive machines and inventions at the Leonardo Da Vinci Exhibition in Rome

The enigmatic smile: between emotion and perception

The smile of the Mona Lisa is perhaps the most celebrated and discussed aspect of the painting because it is not clearly defined, but rather an ambiguous expression that seems to change depending on how it is observed, appearing more serene or more melancholic.

Recent studies have explained that this ambiguity depends in part on the mechanisms of visual perception related to a slightly shaded and blurred (sfumata) region framing the upper part of the lips, which influences the perceived expression.

This oscillation between different emotional states does not appear to be accidental, but intentionally constructed by Leonardo to represent a complex mental condition that can be interpreted differently by every observer.

Mona Lisa meaning
WikiImages/Pixabay

What technique did Leonardo use for the Mona Lisa?

At the heart of the Mona Lisa’s mysterious aura lies the sfumato technique, one of the most innovative elements of Leonardo’s painting style. This technique consists of applying extremely thin, almost impalpable layers of color (glazes), which allow for softening contours and blending the subject with the surrounding atmosphere.

By eliminating sharp outlines, the face becomes more alive, dynamic, and in constant transformation, making the smile appear unstable and giving the impression that her gaze follows the viewer.

By making the edges of the eyes and mouth imprecise, Leonardo represents the way we actually see, forcing our brain to “complete” the image and creating the illusion that the Mona Lisa is changing her expression as we look at her.

The landscape and its symbolic meaning

In the background of the Mona Lisa is a distant and ethereal landscape that amplifies the work’s depth and sense of mystery because it is difficult to identify.

Behind her, one can see trees, a watercourse, and a bridge. Many have wondered where the work was painted, suggesting that the background might represent Ponte Romito or Ponte Buriano, both in the Arezzo area.

In recent times, researcher and medieval historian Carla Gori has proposed that the landscape represents Bobbio, a village in the Piacenza province, a theory supported by studies on trace fossils (ichnofossils).

However, since Leonardo rarely copied a precise location exactly, it is likely that the landscape is an imaginary synthesis serving as a metaphor for the relationship between man and nature, or a symbol of time and transformation.

Mona Lisa landscape
Bobbio (nonmisvegliate/Pixabay)

Psychological interpretations

Over time, the portrait of the Mona Lisa has also been the subject of psychological interpretations. Sigmund Freud, for example, interpreted the smile as a subconscious reference to the mother figure, a hypothesis echoed in some modern readings of the work.

As previously noted, studies in neuroscience and the psychology of perception have suggested that the ambiguity of the expression depends on how the brain organizes visual information, confirming once again the profound link between art and science in Leonardo’s work.

The Mona Lisa today: From Renaissance ideal to global icon

From a historical perspective, the Mona Lisa represents a model of the Renaissance portrait. The pose, the calm expression, and the balanced composition reflect the values of the era: harmony, restraint, and the centrality of the human being. However, Leonardo introduced a new element: he did not limit himself to representing external appearance but sought to suggest the inner dimension and complexity of the person.

Today, the Mona Lisa is a global cultural icon. Her fame is also tied to historical events like the theft of 1911, which helped make her famous worldwide.

Displayed at the Louvre in a protected glass case and visited by millions of people every year, she has become a universal symbol, reproduced, reinterpreted, and cited in every field of visual culture.

This stratification of historical, artistic, psychological, and cultural meanings has made the Gioconda an inexhaustible work, capable of continuing to challenge and intrigue anyone who gazes upon her.

Leonardo Live

Visit the Leonardo Da Vinci Exhibition in Rome and discover his machines, inventions, and much more first-hand.

You can read the Italian version of this article here >